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Matthew Herper of Forbes wrote that the attempted hostile takeover was "done for the specific purpose of firing the company’s management and stopping a proposed merger with Allos Therapeutics.

Shkreli is also the CEO of start-up software company Gödel Systems, which he founded in August 2016.On February 1, 2011, in a naked short sale on an account it held with Merrill Lynch, MSMB Capital sold short 32 million shares of Orexigen Therapeutics stock at about .50 per share the day after its price plunged from .09, when the Food and Drug Administration (FDA) declined to approve the drug Contrave.Merrill Lynch lost million on the trade and MSMB Capital was virtually wiped out. "When she arrived I knew then that I really did have a charmed, blessed life.Seventeen people drowned and he barely made it to the riverbank after suffering from hypothermia, shock, bruises and a broken arm.

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